No1(1) 2018
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DOI 10.37219/2528-8253-2018-1-45 |
Kishchuk VV, Grytsun JP
Forms of scleroma – influence on the patients quality of life
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Kishchuk Vasyl V.
Vinnitsya National Pirogov Memorial Medical University
Department of Otolaryngology, Head of Department
Doctor of Medical Sciences, Professor
E-mail: kvv4488@ukr.net
Orchid ID: http://orcid.org/0000-0002-3390-2401
Gritsun Yaroslav P.
Vinnitsya National Pirogov Memorial Medical University
Department of Otolaryngology
Assistant of the department |
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Abstract
Introduction. Despite world practice that problem of studying the
quality of life in patients with scleroma remains virtually uninvestigated.
Therefore the purpose of our study was to investigate changes in the quality
of life of patients with scleroma and to evaluate this indicator in patients
with different forms of the disease.
Materials and methods. There have been examined 92 patients (33
males, 59 females) with scleroma at the age from 23 to 79 years (at an
average 53,5±14,57 years) and the duration of the disease from 1 to 48 years
(at an average 17,63±11,94 years). The study of patients included assessment
of complaints, general clinical score, results of examination of ENT-organs,
endoscopy of larynx, trachea, bronchi. Quality of life indices were
determined from enquirer Short version of Health enquirer – 36 (The MOS
36-item Short Form Health Survey – SF-36) in the following groups: 1)
comparison group – apparently healthy persons (n=20); 2) patients with
predominantly infiltrative form of scleroma (n=31); 3) patients with
predominantly atrophic form of the disease (n=30); 4) patients with
predominantly cicatricial form (n=31).
Results. The quality of life of patients with scleroma is accompanied
by a significant decrease of an average of 18,4% compared with healthy
individuals, mainly due to the physical component of health. Comparing the
data of patients with predominantly infiltrative form of scleroma and
healthy persons (control), significant differences were observed in the
indicators of physical functioning (68,77±24,79% versus 93,75±7,58%; p
<0,001) and social activity (69,22±25,97% versus 86,24±18,54%; p=0,014).
This indicates the effect of the disease on the ability to with stand the
physical activity during the day and the presence of problems in
communicating with other people already at the initial stages of the
disease. Mostly atrophic and cicatricial forms of scleroma lead to the most
significant decrease in physical (39,35±10,89% and 37,26±9,73%,
respectively) and the mental component of health (42,27±10,04% and
36,39±6,8%), as compared with healthy individuals and patients with
predominantly infiltrative disease.
Conclusions. The study of the quality of life of patients with
scleroma in clinical practice allows to determine the disease effect on the
physical, psychological and social functioning of the patient and, along
with the general clinical methods of the study, allows us to give a
comprehensive assessment of the patient's condition and the effectiveness of
his treatment. |
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Keywords
scleroma, quality of life. |
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