No2-3(2) 2019
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DOI 10.37219/2528-8253-2019-2-04 |
Shydlovska TA, Shydlovska TV, Petruk LG
Correlation between the main parameters SLAEP and rheoencephalography in
patients with acoustic trauma
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Shidlovskaya Tetiana A.
State Institution “Institute of otolaryngology named after Prof. O.S.
Kolomiychenko of the National Academy of Medical Sciences of Ukraine”; Kyiv,
Ukraine.
Chief Researcher, Laboratory for Occupational Voice and Hearing Disorders
(with phoniatrics group)
Doctor of Medical Sciences, Professor
E-mail: doctor_sh@ukr.net.
Orchid ID: https://orcid.org/0000-0002-7894-359X
Shidlovskaya Tamara V.
State Institution “Institute of otolaryngology named after Prof. O.S.
Kolomiychenko of the National Academy of Medical Sciences of Ukraine”; Kyiv,
Ukraine.
Laboratory for Occupational Voice and Hearing Disorders (with phoniatrics
group)
Doctor of Medical Sciences, Professor
E-mail: doctor_sh@ukr.net
Petruk Lyubov G.
Military Medical Clinical Center of the Southern Region
Department of Otorhinolaryngology
PhD
E-mail: amtc@kndio.kiev.ua
Orchid ID: http://orcid.org/0000-0002-1261-7054 |
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Abstract
It is known that vascular factor is one of the main factors of occurrence
and development of SHL of any etiology. Our previous studies have shown that
this statement is also true in relation to sensorineural disorders that
occur in acoustic trauma. With acoustic trauma, both peripheral and central
– the brainstem and cortical departments of the auditory analyzer suffer. At
the same time, in terms of clarifying the topic of the lesion of the
auditory system, the temporal characteristics of the SLAEP are very
informative, which allow to identify violations in the brainstem structures
of the auditory analyzer, including those in the early stages. On the other
hand, it is known that the correlation analysis of the results of
instrumental studies is very important in relation to the characteristics of
the relationship between certain indicators that characterize the relevant
processes.
The purpose of the study is to determine the correlation coefficients
between the temporal indices of SLAEP and
quantitative values of rheoencephalography data to clarify the relationship
(correlation) between the state of the brains-
tem structures of the auditory analyzer and cerebral blood circulation in
the carotid and vertebrobasilar systems in pa-
tients with acoustic trauma.
Materials and methods: to achieve this aim, we examined 71 patients
with acoustic trauma at the age of 19-50 years, with predominantly bilateral
asymmetric sensorineural disorders, a descending type of audiometric curve,
a moderate degree of decrease in auditory function, the most pronounced
significant (P<0.01) increase in hearing thresholds to tones 4, 6 and 8 kHz
on the tonal threshold audiometric curve.
Cerebral blood flow in patients with acoustic trauma was studied by
rheoencephalography using a computer rheograph of the company «DX-systems»
(Ukraine) according to the generally accepted method. Registration of
shortlatency auditory evoked potentials (SLAEP) was carried out using the
analyzing system «Eclipse» of the company «Interacoustics» (Denmark),
according to the generally accepted method.
To identify the correlation between the brainstem structures of the auditory
analyzer and cerebral circulation in the vertebrobasilar and carotid
systems, we took into account the correlation coefficients (r) and their
errors (mr) between the main indicators REG in the carotid and
vertebrobasilar systems, as well as the most informative time indicators
SLEP patients with acoustic trauma.
Results and discussion: We carried out a correlation analysis between
the values of LPP V wave of SLAEP and MPI (I-V) SLAEP, as well as the values
of DCI, DSI and Pi in the carotid and vertebrobasilar systems in servicemen
with combat acoustic trauma. The determination of such a connection is
important because the severity of the lesion of the auditory system and the
prognosis of the effectiveness of therapeutic measures in acoustic trauma
largely depends on the presence and severity of dysfunction in the brainstem
structures of the auditory analyzer. The obtained data confirm the influence
of the state of cerebral circulation on the development of functional
disorders of the cerebrospinal structures of the brain and the auditory
analyzer in acoustic trauma.
There is a direct correlation in the development of such disorders with
changes of the tone of cerebral vessels, but especially - violations of
venous outflow. According to our data, in the carotid system, there is a
weak direct correlation between the value of DCI, reflecting the tone of
cerebral vessels, and LPP V wave of SLAEP (r=0.309; mr=0.063), as well as
MPI I-V SLEP (r=0.322; mr=0.042). A weak direct correlation was also found
between these indicators in the vertebralbasilar system, where the
corresponding correlation coefficients were r=0.385, and mr=0.061, and
r=0.348, and mr=0.036.
Between LPP V - SLAEP and DSI, which characterizes venous outflow, in the
carotid system, r was 0.458 and mr=0.057, and for MPI I-V SLEP the
coefficient was (r=0.463; mr=0.049). A direct correlation between these
indicators was found in the vertebral-basilar system (the corresponding
values were: r=0.516, mr=0.021 and r=0.523, mr=0.022).
Conclusion: Correlation analysis showed the presence of a
relationship between the state of cerebral circulation according to REG in
carotid, and, especially, in the vertebrobasilar systems and temporal
indices of SLAEP in patients with acoustic trauma obtained in real combat
conditions.
In patients with acoustic trauma, a significant inverse correlation was
found between the temporal indices of SLAEP and the values of Ri according
to REG data characterizing the state of pulse blood filling in the
vertebrobasilar pool. Thus, a significant inverse correlation (r=-0,527, mr=0,068)
is observed between the values Ri and the duration of the inter-peak
interval I-V SLAEP, for the duration of the LPP V wave r was -0,512, and mr=0,026.
Only weak direct correlation in both carotid and vertebral-basilar systems
was found with DCI indicators reflecting the state of cerebral vascular tone
in the studied temporal characteristics of SLAEP. This may be due to the
risk of changes in the tone of cerebral vessels (the tendency to both
increase and decrease) in this contingent of patients.
With the value of DSI, which characterizes venous outflow, there is a direct
correlation with both LPP V wave and MPI I-V SLAEP in both systems of
cerebral blood supply. In the carotid system between LPP V SLAEP and DSI, r
was equal to 0.458, and mr=0.057, and between MPI I-V SLAEP and the value of
DSI was (r=0.463; mr=0.049), in the vertebrobasilar system, the
corresponding values were r=0.516, mr=0.021 and r= 0.523, mr=0.022. |
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Keywords
acutrauma, brainstem structures of the auditory analyzer, cerebral
circulation. |
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