No3-4(5) 2022
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DOI 10.37219/2528-8253-2022-3-82 |
Yashan OI, Pokrishko OV, Gerasimyuk МІ, Yashan AO, Buchinskiy PO
Evaluation of the effectiveness of natural oromukos throat spray from
sunflower flower extracts in the treatment of acute pharyngitis in adults |
Yashan Oleksandr I.
I. Horbachevskyy Ternopil National Medical University.
Head of the otolaryngology, ophthalmology and neurosurgery department
Doctor of Medical Sciences, Professor
e-mail: yashan@tdmu.edu.ua
ORCID ID: https://orcid.org/0000-0001-6983-7835
Pokryshko Olena V.
I. Horbachevskyy Ternopil National Medical University.
Associate professor of the microbiology, virology and immunology department
Candidate of Medical Sciences, Associate professor
e-mail: pokryshko@tdmu.edu.ua
ORCID ID: https://orcid.org/0000-0001-9640-0786
Herasymiuk Maksym I.
I. Horbachevskyy Ternopil National Medical University.
Associate professor of the otolaryngology, ophthalmology and neurosurgery
department
Candidate of Medical Sciences, Associate professor
e-mail: herasymyuk_m@tdmu.edu.ua
ORCID ID: https://orcid.org/0000-0001-8566-7426
Yashan Artem O.
I. Horbachevskyy Ternopil National Medical University.
Assistent professor of the otolaryngology, ophthalmology and neurosurgery
department
Master of Medicine
e-mail: Yashanao@tdmu.edu.ua
Buchynskyi Pavlo O.
Resident doctor of the otolaryngology, ophthalmology and neurosurgery
department
I. Horbachevskyy Ternopil National Medical University.
e-mail: buchynskyj_paol@tdmu.edu.ua
ORCID ID: https://orcid.org/0000-0002-8605-4071 |
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Abstract
Acute pharyngitis is a common disease among the adult population. The most
common causative agents of acute inflammatory diseases of the pharynx are
β-hemolytic streptococci.
Oromucous sprays, which are used in this case for treatment, are a special
dosage form that ensures the spraying of particles of the active substance
and their adhesion to the mucous membrane of the oral cavity and pharynx.
The purpose of the study: to determine the therapeutic effect and the
level of bacteriological colonization of the drug "Lorosan" for the
treatment of acute pharyngitis.
Materials and methods: 32 patients, aged from 20 to 27 years, with
symptoms corresponding to the nosological form of acute pharyngitis were
examined. Clinical examination of patients was carried out at the beginning
of the disease and one week after treatment with Lorosan. The clinical
effectiveness of the drug was determined by analyzing changes in complaints
and the condition of the mucous membrane of the oropharynx.
Results: After using the drug "Lorosan" for 7 days, all patients
noted a decrease in pain in the throat, a significant decrease in the
sensation of a foreign object in the throat and the number of secretions,
normalization of the general condition and full recovery of the voice. The
number of caseous tonsillitis in the tonsillar lacunae decreased, and the
unpleasant smell from the mouth disappeared.
The obtained results of the microbiological study of the biomaterial taken
after 7 days of treatment with the drug "Lorosan" showed a sharp decrease in
the number of microorganisms and the level of their spread of the posterior
pharynx.
Thus, the new natural oromucous spray from sunflower is an effective drug in
the monotherapy of acute pharyngitis in adults, as it allows to
significantly reduce the clinical symptoms of the disease and significantly
reduce the bacterial colonization of the oropharynx by the causative agents
of inflammatory processes. |
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Keywords
acute pharyngitis, lorosan, oromucous spray. |
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Reference
- Sykes EA, Wu V, Beyea MM, Simpson MTW, Beyea JA. Pharyngitis:
Approach to diagnosis and treatment. Can Fam Physician. 2020;66(4):
251-7.
- Soderholm AT, Barnett TC, Sweet MJ, Walker MJ. Group A streptococcal
pharyngitis: Immune responses involved in bacterial clearance and
GAS-associated immunopathologies. J Leukoc Biol. 2018;103(2):193-213.
doi: 10.1189/jlb.4MR06 17-227RR.
- Oliver J, Wadu EM, Pierse N, Moreland NJ, Williamson DA, Baker MG.
Group A Streptococcus pharyngitis and pharyngeal carriage: A
metaanalysis. PLoS Negl Trop Dis. 2018;12(3): e0006335. doi:
10.1371/journal.pntd.0006335.
- Bisno AL, Gerber MA, Gwaltney JM Jr, Kaplan EL, Schwartz RH.
Practice guidelines for the diagnosis and management of group A
streptococcal pharyngitis. Infectious Diseases Society of America. Clin
Infect Dis. 2002;35(2):113-25. doi: 10.1086/340949.
- Sokolova OO. [Pharmacognostic study of sunflower (Helianthus annuus
L.) herbal drugs and the development of herbal medicinal products on its
basis] [dissertation]. Kharkiv; 2019: 23 p. [In Ukrainian].
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