No5(5) 2022
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DOI 10.37219/2528-8253-2022-5-81 |
Molochek Y, Fediuk O
Evaluation of the clinical efficiency of topical antibacterial therapy of
chronic nasopharyngitis after adenotomy |
Molochek Yuri
National specialized children's hospital Ministry of Health of Ukraine OHMATDYT
ENT (Ear, Nose, Throat): Pediatric Otolaryngology
Division Chief
E-mail: y.molochek@gmail.com
Fediuk Oleksii
National specialized children's hospital Ministry of Health of Ukraine OHMATDYT
ENT (Ear, Nose, Throat): Pediatric Otolaryngology
E-mail: alexey.fediuk@gmail.com |
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Abstract
The presented article provides research, analysis and discussion regarding
the rationality and clinical effectiveness of topical antibacterial therapy
for chronic nasopharyngitis after adenotomy, in particular the effectiveness
of the drug Izofra. Thanks to the study, the effectiveness of the drug
Izofra in the postoperative period was substantiated and analysed. The
authors obtained valuable information, knowledge and experience thanks to a
randomized sample study with the main and control groups, namely,
confirmation of the pronounced anti-inflammatory, antibacterial effect of
the drug Izofra and its objective rationality of use. Significant reduction
of inflammation, reduction of edema, improvement of secretion rheology and
increase of local immunity after use of the drug Izofra have been studied
and analysed. The topical antibacterial, anti-inflammatory, anti-edematous
effect and eradication of planktonic forms of microorganisms (biofilms) of
the drug Izofra clinically demonstrated a decrease in the level of
postoperative complications, chronicity of the process, relapses and
improvement of the postoperative course of treatment of children. |
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Keywords
chronic nasopharyngitis, adenotomy, local therapy, Izofra, topical
antibacterial therapy. |
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Reference
- Fokkens WJ, Lund VJ, Hopkins C, Hellings PW, Kern R, Reitsma S. et
al. European Position Paper on Rhinosinusitis and Nasal Polyps 2020.
Rhinology. 2020;58(Suppl S29):1-464. doi: 10.4193/Rhin20.600.
- Mardikasari SA, Sipos B, Csуka I, Katona G. Nasal route for
antibiotics delivery: Advances, challenges and future opportunities
applying the quality by design concepts. Journal of Drug Delivery
Science and Technology. 2022;77.
https://doi.org/10.1016/j.jddst.2022.103887.
- Soldatskiĭ IL, Denisova OA, Ivanenko AM. [The
comparative effectiveness of framycetin included
in combined therapy of adenoiditis in the children]. Vestn Otorinolaringol. 2014;(5):69-71.
- Instructions for the medical use of ISOFRA.
Available from: https://mozdocs.kiev.ua/likiview.php?id=2929.
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