No3(3) 2020
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DOI 10.37219/2528-8253-2020-3-38 |
Bezshapochnyy S.B., Loburets V.V., Loburets A.V., Dzhirov O.R.,
Podovzhny O.G.
Options for local therapy of chronic tonsillopharyngitis to achieve a
long-term remission |
Bezshapochny Sergey B.
Ukrainian Medical Dental Academy
Head of Department of Otolaryngology
Doctor of Medical Sciences, Professor.
Email: bezshapochny@ukr.net
https://orcid.org/0000-0002-8726-2024
Loburets Valery V.
Ukrainian Medical Stomatological Academy
Department of Otolaryngology with Ophthalmology
PhD, Docent
Email: umsalor@gmail.com
http://orcid.org/0000-0001-8538-9649
Loburets Andrey V.
Ukrainian Medical Stomatological Academy
Department of Otolaryngology with Ophthalmology
PhD, Assistant of the department
E-mail: anjeyloburets@gmail.com
http://orcid.org/0000-0003-4164-0816
Dzhirov O.R.
Ukrainian Medical Stomatological Academy
Department of Otolaryngology with Ophthalmology
Podovzhny Olexander G.
Ukrainian Medical Stomatological Academy
Department of Otolaryngology with Ophthalmology
PhD, Docent
E-mail: umsalor@gmail.com
https://orcid.org/0000-0002-5035-0450 |
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Abstract Topicality: Chronic tonsillopharyngitis is
one of the most common diseases of the upper respiratory tract.
Although more and more physicians are preferring modern non-surgical
treatments and abandoning the use of surgery to treat chronic compensated
tonsillopharyngitis, there is still no consensus on approaches to
conservative therapy.
One of the modern methods of controlling the microflora of the oral cavity
is the use of lantibiotics. This creates competitive pressure of endogenous
opportunistic flora and viruses, preventing episodes of disease recurrence.
The relevance of our study is due to the need to optimize and improve
pharmacotherapy, not only during the exacerbation of the disease, but also
to form a stable remission, which will significantly improve the quality of
life of patients.
Materials and methods: A total of 36 patients were observed in the
study, who were divided into two groups with different treatments. Group 1
received classical therapy, including local sanitation of the tonsils by was
hing the gaps with NaCl solution 0.9% daily from the first visit until the
7th day and taking topical combination drugs (antiseptic, local nonsteroidal
anti-inflammatory drug – benzydamine) for 1 tab. 3 times a day for 7 days.
Group 2, if necessary, received washing the lacunae of the tonsils with a
solution of 0.9% NaCl, and took an oral probiotic Baсtoblis (S. salivarius
K12) 1 tab. at night for 1 month according to the instructions.
The McIsaac scale and microbiological examination of pharyngeal smears were
used to establish the clinical diagnosis.
Results: On the seventh day of treatment, there is a rapid
improvement in the well being of patients in both groups. In the first group
there is a more effective elimination of pain symptoms and in the second
group of bad breath. However, at the time of the 16th week from the start of
treatment, in the first group due to more frequent recurrences of the
disease, there is a significant deterioration in all indicators.
The results of the microbiological study revealed a significant reduction in
the colonization of the oropharyngeal cavity by pathogenic strains of
staphylococci and Escherichia coli in group 2 at 16 weeks after treatment.
Conclusion: Based of the study, it can be concluded tht bacterial
therapy has shown significant effectiveness in achieving long-term remission
in contrast to the other study group, which was effective only during the
acute period of the disease. |
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Keywords
Tonsilopharyngitis, chronic tonsillitis, Streptococcus salivarius K12,
Bactoblis, probiotics. |
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